I have had several cortisone injections to the knees, elbow, and shoulder. I have experienced face flushes and sweating, but this goes away after a couple of days. And the relief is worth it.

I had two cortisone injections with MRI in February of 2012 for neck pain and headaches. The next day, I had heart palpitations, my blood pressure consistently was in the 210/120 range, and I had a pulse of 129. I visited the ER and they said there was no connection with the cortisone and it was probably anxiety after the heart attack was ruled out. I now have to have the same thing again in 10 days after the symptoms have worsened again, having been much better for the first five weeks.

I have rheumatoid arthritis (RA) and have had cortisone injections in my left knee with much success. I need total knee replacements in both knees and had cortisone shots in both knees today to buy me some time. The right knee hurt like the devil when the medicine went in and still hurts six hours later. This is the first injection in that particular knee. I am resting and icing it!

I hate cortisone shots in both knees, which were stiff for about 12 hours. I didn't sleep that night, but now my knees are feeling better and I plan on going for a walk.

I have had severe pain in my hips for two years and cortisone shots always work with no side effects except once and they told me to put ice packs on it the first day, which did help. I get the shots every six months and I swear by them.

One day after a cortisone injection into my right knee, I experienced heart palpitations and a flushed face. I was unable to sleep and felt irritable throughout the day.

A couple of months ago, I received a cortisone injection in my left shoulder. Before that, I was off work for 10 days because of the excruciating pain. I returned to work the day after I got the injection. I could not believe the difference. I still occasionally have mild pain, but at least I can use my arm now. I have had no side effects. Getting the injection was quite painful but well worth it.

I had a cortisone injection in my left knee two days ago. I have had these injections in my right knee with no ill effects. Yesterday, I started with a headache that got increasingly worse, and then I turned bright red from my shoulder blades around to my chest and up to my hairline. I itched all over intermittently, and I had slightly blurry vision. I was/am slightly nauseated. I wasn't able to sleep. I've taken Benadryl and acetaminophen, and they haven't helped much.

I had a cortisone injection over two weeks ago. It worked on my lumbar back pain, but I have had heart palpitations at night, trouble sleeping, and at times notice bouts of deep depression.