Coronary Balloon Angioplasty and Stents
(Percutaneous Coronary Intervention, PCI)
Medical Author: Daniel
Kulick, MD, FACC, FSCAI
Medical Editor: Melissa Conrad Stöppler, MD
What is balloon angioplasty?
Balloon angioplasty of the coronary artery, or percutaneous transluminal coronary angioplasty (PTCA), was introduced in the late 1970's. PTCA is a non-surgical procedure that relieves narrowing and obstruction of the arteries to the muscle of the heart (coronary arteries). This allows more blood and oxygen to be delivered to the heart muscle.
PTCA, is now referred to as percutaneous coronary intervention, or PCI, as this
term includes the use of balloons, stents, and atherectomy devices. PCI is accomplished with a small balloon catheter inserted into an artery in the groin or arm, and advanced to the narrowing in the coronary artery. The balloon is then inflated to enlarge the narrowing in the artery. When successful,
PCI can relieve chest pain of angina, improve the prognosis of patients with unstable angina, and minimize or stop a heart attack without having the patient undergo open heart coronary artery bypass graft (CABG) surgery.
In addition to the use of simple balloon angioplasty, the availability of stainless steel stents, in a wire-mesh design, have expanded the spectrum of patients suitable for
PCI, as well as enhanced the safety and long-term results of the procedure. Since the early 1990's, more and more patients are treated with stents, which are delivered with a
PCI balloon, but remain in the artery as a "scaffold". This procedure has markedly reduced the numbers of patients needing emergency CABG to below 1%, and particularly with the use of the new "medicated" stents (stents coated with medications that help prevent plaque formation), has reduced the rate of recurrence of the blockage in the coronary artery ("restenosis") to well below 10%. At present, the only patients treated with just balloon angioplasty are those with vessels less than 2mm (the smallest diameter stent), certain types of lesions involving branches of coronary arteries, those with scar tissue in old stents, or those who cannot take the blood thinner medication known as clopidogrel bisulfate (Plavix). Various "atherectomy" (plaque removal) devices were initially developed as adjuncts to
PCI. These include the use of the excimer laser for photoablation of plaque, rotational atherectomy (use of a high-speed diamond-encrusted drill) for mechanical ablation of plaque, and directional atherectomy for cutting and removal of plaque. Such devices were initially thought to decrease the incidence of restenosis, but in clinical trials were shown to be of little benefit, and now are only used in selective cases as an adjunct to standard PCI (precutaneous artery intervention).
Next: How does coronary artery disease develop? »
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