CONJUGATED ESTROGENS/MEDROXYPROGESTERONE- ORAL (cont.)
DRUG INTERACTIONS: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: aminoglutethimide, corticosteroids (e.g., prednisone), hydantoins (e.g., phenytoin), warfarin, drugs which affect certain liver enzymes (CYP450-3A4 enzymes) such as azole antifungals (e.g., ketoconazole, itraconazole), carbamazepine, macrolide antibiotics (e.g., clarithromycin, erythromycin), phenobarbital, rifamycins (e.g., rifampin), ritonavir, cimetidine, St. John's Wort. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe nausea/vomiting or excessive vaginal bleeding.
NOTES: Do not share this medication with others. Keep all appointments with your doctor and the laboratory. You should have a complete physical examination that includes blood pressure measurements and breast/pelvic examinations at regular intervals (e.g., once a year) or as directed by your doctor. Follow your doctor's instructions on how to examine your own breasts and report any lumps immediately. You should also be regularly screened for cervical cancer (e.g., Pap test) and have periodic mammograms as determined by your doctor. Consult your doctor for more details. Non-drug therapy to help prevent bone loss includes a weight-bearing exercise plan and adequate daily calcium and vitamin D. Consult your doctor or pharmacist for more details.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Last Editorial Review: 3/2/2005
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