conjugated estrogens vaginal cream, Premarin Vaginal Cream

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GENERIC NAME: conjugated estrogens vaginal cream

BRAND NAME: Premarin Vaginal Cream

DRUG CLASS AND MECHANISM: Estrogens are one of the two major classes of female hormones. (Progestins comprise the second major class). Estrogens are used primarily to treat the symptoms of menopause and states in which there is a deficiency of estrogen, for example, among women who have had their estrogen-producing ovaries removed. Conjugated estrogens are a mixture of several different estrogens (estrogen salts) that are derived from natural sources and blended to approximate the composition of estrogens in the urine of pregnant horses. The main components are sodium estrone sulphate and sodium equilin sulfate. Estrogens have widespread effects on tissues in the body. Estrogens cause growth and development of the female sexual organs and maintain female sexual characteristics such as the growth of underarm and pubic hair, body contours, and skeleton. Estrogens also increase secretions from the cervix and growth of the inner lining of the uterus (endometrium). Conjugated estrogens were first approved by the FDA in 1938.

GENERIC AVAILABLE: No

PRESCRIPTION: Yes

PREPARATIONS: 0.625 mg/gram

STORAGE: The cream should be stored at room temperature, 15-30 C (59-86 F).

PRESCRIBED FOR: Premarin vaginal cream is used for the relief of vaginal symptoms in postmenopausal women who have developed uncomfortable vaginal dryness, inflammation, or painful intercourse due to atrophy of the vagina and/or vulvae.




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