Gardner's Syndrome (Familial Adenomatous Polyposis) »
What is familial adenomatous polyposis?
Familial adenomatous polyposis (FAP) is an inherited disorder
characterized by cancer of the
large intestine (colon) and
rectum. People with the classic type of familial adenomatous polyposis may
begin to develop multiple noncancerous (benign)
growths (polyps) in the colon as early as their
teenage years. Unless the
colon is removed, these polyps will become malignant (cancerous). The average
age at which an individual develops colon cancer in classic familial adenomatous
polyposis is 39 years. Some people have a variant of the disorder, called
attenuated familial adenomatous polyposis, in which
polyp growth is delayed. The
average age of colorectal cancer onset for attenuated familial adenomatous
polyposis is 55 years.
In people with classic familial adenomatous polyposis, the number of polyps
increases with age, and hundreds to thousands of polyps can develop in the
colon. Also of pa...
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