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Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. Other side effects include convulsions, paralysis, and death. There have been reports of death following ingestion of just 1-1/2 teaspoons of the powder.
In case of poisoning, a dilute tannic acid solution should be taken, followed by large quantities of drinks that contain eggs (albuminous drinks).
Special Precautions & Warnings:Pregnancy and breast-feeding: Colocynth is UNSAFE. Don't take it.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.