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GENERIC NAME: COLLAGENASE OINT - TOPICAL (coal-ADGE-ih-naze)

BRAND NAME(S): Santyl

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication breaks up and helps remove dead skin and tissue to promote healing. It is used to aid healing of burns and skin ulcers.

HOW TO USE: This medication is for use on the skin only. To apply, first clean the area as directed. If an antibiotic ointment is prescribed, apply it next as directed. Then, using a wooden spatula for deep wounds or a gauze pad for shallow wounds, apply the ointment directly to the affected area and bandage securely. Avoid use near the eyes and be careful not to get the ointment outside the affected area. Wash hands thoroughly after applying the ointment.

SIDE EFFECTS: This medication is generally well tolerated when used as directed. Redness or irritation may occur to surrounding skin. If this continues or becomes bothersome, inform your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor if you have: other illnesses, allergies (especially drug allergies). This medication should be used only if clearly needed during pregnancy or while breast-feeding. Discuss the risks and benefits with your doctor.

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may use, especially of: other skin products. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. This medicine may be harmful if swallowed.

NOTES: If the condition for which this was prescribed does not appear to improve after a few days, notify your health care professional.

MISSED DOSE: If you miss a dose, apply it as soon as remembered and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) as directed. Keep this and all medication out of the reach of children.


Last Editorial Review: 3/2/2005




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collagenase oint-topical, Santyl

What is a peptic ulcer?

A peptic ulcer is a hole in the gut lining of the stomach, duodenum, or esophagus. A peptic ulcer of the stomach is called a gastric ulcer; of the duodenum, a duodenal ulcer; and of the esophagus, an esophageal ulcer. An ulcer occurs when the lining of these organs is corroded by the acidic digestive juices which are secreted by the stomach cells. Peptic ulcer disease is common, affecting millions of Americans yearly. The medical cost of treating peptic ulcer and its complications runs in the billions of dollars annually. Recent medical advances have increased our understanding of ulcer formation. Improved and expanded treatment options are now available.

What are the causes of peptic ulcers?

For many years, excess acid was believed to be the major cause of ulcer disease. Accordingly, treatment emphasis was on neutra...

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