DRUG INTERACTIONS: Inform your doctor about all the medicines you use (both prescription and nonprescription), especially of: methotrexate, penicillin-like antibiotics, cephalosporins (e.g., cephalexin), oral diabetes medicines, indomethacin, nitrofurantoin. Aspirin and salicylate-type medicines can prevent probenecid from being fully effective. It is best to avoid these products. If you are to take a urine test while using this medication, tell the doctor or laboratory personnel that you are taking colchicine because colchicine may affect the test results. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include nausea; vomiting; diarrhea; stomach pain; burning pain in throat, stomach, and skin; blood in urine; and muscle weakness.

NOTES: This drug relieves pain but only pain associated with gout. It should not be used for any other type of pain. Do not allow anyone else to take this medication.

MISSED DOSE: If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from sunlight and moisture.

Suggested Reading by Our Doctors

• Gout - Gout and hyperuricemia are caused by uric acid crystals building up in the body. Read how diet changes--avoiding alcohol and high purine foods--prevent painful attacks and gout pain.

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