colchicine/probenecid - oral, Col-Benemid (cont.)
HOW TO USE: Take this medication by mouth, usually twice daily with a full glass of water (8 ounces/240 milliliters) or as directed by your doctor. If stomach upset occurs, this medication may be taken with food or antacid. To prevent kidney stones while taking this drug, drink plenty of fluids throughout the day unless your doctor directs you otherwise. Taking products such as sodium bicarbonate and avoiding large amounts of vitamin C can also help reduce your risk for kidney stones. Ask your doctor for more details.The dosage is based on your medical condition and response to treatment. To reduce your risk for serious side effects, do not increase your dose, take it more frequently, or take it for a longer time than directed by your doctor. Your doctor may start you on a lower dose and adjust your dose during treatment with this medication.After starting this medication, you may have an increase in the number of gout attacks while your body gets rid of extra uric acid. This may last for several months until the uric acid in your blood is lowered. Do not stop taking this drug if you have a sudden gout attack. Continue taking it along with the medications (such as colchicine, ibuprofen, indomethacin) prescribed by your doctor for gout pain.Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.Tell your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS: Nausea, cramping, diarrhea, loss of appetite, dizziness, hair loss, headache, vomiting, and frequent urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these rare but serious side effects occur: muscle weakness or pain, numbness/tingling in your fingers or toes, pale or gray color of the lips/tongue/palms of hands, persistent nausea/vomiting, severe diarrhea, severe stomach/abdominal pain, signs of infection (such as fever, persistent sore throat), unusual bleeding/bruising, unusual weakness/tiredness, dark urine, yellowing eyes/skin.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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