GENERIC NAME: COLCHICINE WITH PROBENECID - ORAL (COAL-cheh-seen WITH pro-BEN-uh-sid)
BRAND NAME(S): Col-Benemid, Col-Probenecid
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is a combination of colchicine and probenecid. Colchicine is used in the treatment of gout. It relieves the pain of gout and helps prevent further attacks. Probenecid helps clear the body of uric acid which is increased in cases of gout. The combination is effective in the treatment of gout.
HOW TO USE: This medication is taken after an acute attack of gout has ended. It will not relieve an attack in progress. While taking this medication, drink at least six to eight 8 oz glasses of fluid a day to help prevent development of kidney stones. To help relieve stomach upset, this medication may be taken with food or antacids.
SIDE EFFECTS: Stomach pain, loss of appetite, nausea, or vomiting may occur as your body adjusts to the medication. Inform your doctor if these effects persist or become bothersome. Notify your doctor if you develop: yellowing of the eyes or skin, sore throat, easy bruising or bleeding, muscle aches, numbness or tingling of legs and arms, fatigue, rash, fever, sore gums, breathing difficulties, itchy skin. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Alcohol can decrease the effectiveness of this medication. Limit alcohol consumption while taking this. Before having surgery, including dental surgery, tell your doctor you are taking colchicine with probenecid. If you have kidney, stomach, intestinal, heart or bleeding disorder problems, tell your doctor before you take this drug. The colchicine in this combination product is not recommended for use during pregnancy. Consult your doctor before using this medication. Colchicine passes into breast milk, though the effects on a nursing infant are in question. Consult your doctor before you breast-feed.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Gout - Gout and hyperuricemia are caused by uric acid crystals building up in the body. Read how diet changes--avoiding alcohol and high purine foods--prevent painful attacks and gout pain.
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