colchicine, Colcrys (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Combining colchicine with statins, for example atorvastatin (Lipitor), simvastatin (Zocor), and lovastatin (Mevacor), Lopid (gemfibrozil), or fenofibrate increases the risk of muscle related adverse effects because these drugs also cause muscle related side effects.

PREGNANCY: There are no adequate studies of colchicine in pregnant women. Colchicine crosses the placenta, and animal studies suggest that colchicine is harmful to the developing fetus; however, their are no reports that contain miscarriage, still births, or harmful effects to the fetus when pregnant women used colchicine for treating FMF. Nevertheless, colchicine should only be used during pregnancy if the benefit justifies the risk to the fetus.

NURSING MOTHERS: Colchicine is excreted into human milk and may cause adverse effects in the infant.

Medically reviewed by Eni Williams, PharmD

Reference: Colcrys FDA Prescribing Information

Medically Reviewed by a Doctor on 12/26/2014

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