GENERIC NAME: colchicine
BRAND NAME: Colcrys, Mitigare
GENERIC AVAILABLE: No
USES: Colchicine is used for the treatment of acute flares of gout. It also is used for treating FMF in adults and children 4 years of age or older. Other unapproved uses of colchicine include treatment of pseudogout, amyloidosis, and scleroderma. These unapproved uses of colchicine require further evaluation.
WARNING: Colchicine can damage the bone marrow causing severe anemia, low white blood counts, and low platelets. Reduced white blood cell counts may increase the risk of infections. All patients taking colchicine long-term require monitoring of their blood counts.
Colchicine also may cause muscle pain (myopathy) or severe muscle breakdown (rhabdomyolysis). Patients with renal or liver dysfunction or taking some other drugs (for example, simvastatin and other statins, gemfibrozil, fenofibrate), which also affect muscle tissue, are at a higher risk of developing rhabdomyolysis.
SIDE EFFECTS: The most common side effects of colchicine are dose-related and include:
- abdominal pain, and
- diarrhea. Colchicine also may
- cause hair loss,
- weakness, and
- nerve irritation.
Quick GuideGout Attack Symptoms, Causes, Treatment, and Diet
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