SIDE EFFECTS: Stomach pain, nausea, diarrhea and vomiting may occur as your body adjusts to the medication. Inform your doctor if these effects persist for 3 hours or longer after you have stopped taking colchicine. Contact your doctor immediately if you experience pain, redness or swelling at the place of injection. Notify your doctor if you develop: yellowing of the eyes or skin, sore throat, fever, chills, easy bruising or bleeding, muscle weakness, numbness or tingling of hands or feet, fatigue, skin rash, bloody urine, diarrhea, burning feeling in stomach/skin or throat. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Alcohol can decrease the effectiveness of this medication. Limit alcohol consumption while taking this. Tell your doctor your medical history, especially of: kidney problems, stomach or intestinal problems, heart problems, bleeding disorders. Before having surgery, including dental surgery, tell your doctor you are taking colchicine. Colchicine is not recommended for use during pregnancy. Consult your doctor for details. This medication passes into breast milk. The effects on a nursing infant are in question. Consult your doctor before you breast-feed.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medications you may use, especially of: NSAID (e.g., ibuprofen, naproxen, phenylbutazone). If you are to take a urine test while using this medication, tell the doctor or laboratory personnel that you are taking colchicine because colchicine may affect the test results.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Colchicine relieves pain but only pain associated with gout. It should not be used for any other type of pain. Do not allow anyone else to take this medication.

MISSED DOSE: If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from sunlight.

Last Editorial Review: 3/2/2005

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