COENZYME Q10 (ubiquinone, ubidecarenone) - ORAL side effects, medical uses, and drug interactions.

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coenzyme Q10 (ubiquinone, ubidecarenone)-oral (cont.)

DRUG INTERACTIONS: Before using this product, tell your doctor or pharmacist of all prescription and nonprescription medications you may use, especially of: drugs that treat high cholesterol (e.g., atorvastatin, lovastatin, gemfibrozil), beta-blockers (e.g., propranolol), diabetes medicines (e.g., insulin), "blood thinners" (e.g., warfarin).

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: This product may lower blood sugar. If you are diabetic, check your blood or urine sugar regularly (daily or as directed). Other laboratory tests may be performed to monitor your progress.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Refer to storage information printed on the package. If you have any questions about storage, ask your pharmacist.

Last Editorial Review: 3/2/2005

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Important Safety Information

KAPIDEX may not be right for everyone. You should not take KAPIDEX if you are allergic to KAPIDEX or any of its ingredients. Severe allergic reactions have been reported.

Symptom relief does not rule out other serious stomach conditions.

The most common side effects of KAPIDEX were diarrhea (4.8%), stomach pain (4.0%), nausea (2.9%), common cold (1.9%), vomiting (1.6%), and gas (1.6%). KAPIDEX and certain other medicines can affect each other. Before taking KAPIDEX, tell your doctor if you are taking ampicillin, atazanavir, digoxin, iron, ketoconazole, or tacrolimus. If you are taking KAPIDEX with warfarin, you may need to be monitored because serious risks could occur.

Uses of KAPIDEX

Persistent heartburn two or more days a week, despite treatment and diet changes, could be acid reflux disease (ARD). Prescription KAPIDEX capsules are used in adults to treat heartburn related to ARD, to heal acid-related damage to the lining of the esophagus (called erosive esophagitis or EE), and to stop EE from coming back. Individual results may vary. Most damage (erosions) heals in 4�8 weeks.

Talk to your doctor or healthcare professional. Please see full Prescribing Information for KAPIDEX.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

KAPIDEX™ is a trademark of Takeda Pharmaceuticals North America, Inc., and is used under license by Takeda Pharmaceuticals America, Inc.

LPD-00767

coenzyme Q10 (ubiquinone, ubidecarenone)-oral (cont.)

One Pill a Day: Up to 24 Hours of Heartburn Relief in Many Adults with ARD

Important Safety Information

Uses of KAPIDEX

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