PRECAUTIONS: Tell your doctor your medical history, especially of: kidney or liver disease, ulcers/intestinal disease, thyroid disease, Addison's disease, prostate or urinary trouble, a history of drug dependency, asthma, nasal polyps, bleeding disorders, any allergies. Because this medication contains aspirin, children and teenagers should not take this drug if they have chickenpox, influenza or any undiagnosed illness without first consulting a doctor about Reye's syndrome, a rare but serious illness. Use caution performing tasks requiring alertness if this medication causes you to feel drowsy. Limit alcohol intake. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. This medicine may cause stomach bleeding. Daily use of alcohol, especially when combined with this medicine, may increase your risk for stomach bleeding. Check with your doctor or pharmacist for more information. Aspirin is not recommended for use during pregnancy. Consult your doctor before using this medication. This medication is excreted into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all over-the-counter and prescription medication you use, including: antidepressants, anti-anxiety drugs, anti-seizure drugs, other narcotic pain relievers, non-narcotic pain medications, sleeping pills, sedatives, blood thinners (anticoagulants and antiplatelet drugs such as warfarin, heparin, NSAID), corticosteroids (e.g., prednisone), methotrexate, cimetidine. Aspirin is an ingredient in many over-the-counter products. To prevent an overdose of aspirin, read the labels carefully before taking other pain relievers or cold products to be sure they do not contain aspirin. Consult your pharmacist if you are uncertain your over-the-counter products contain aspirin. This medication contains caffeine. Avoid drinking large amounts of caffeinated beverages while taking this medication as excessive nervousness and irritability can occur. Do not start or stop any medicine without doctor or pharmacist approval.