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cocaine hydrochloride - topical (cont.)

PRECAUTIONS: Before your procedure, tell your doctor or pharmacist if you are allergic to cocaine; or to other ester-type anesthetics (e.g., benzocaine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: high blood pressure, heart disease (e.g., chest pain, heart attack, irregular heartbeat), overactive thyroid (hyperthyroidism), seizures, infection/sores/injury in the area of the application site (e.g., mouth, nose, throat).This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Caution is advised when using this drug in children because they may be more sensitive to the effects of the drug, especially restlessness/excitement.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially irregular heartbeat and chest pain.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before and during treatment with this medication. In some cases, a serious (possibly fatal) drug interaction may occur.If you are currently using any of these medications listed above, tell your doctor or pharmacist before using this medication.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: stimulant-type drugs (e.g., catecholamines such as norepinephrine or epinephrine, ephedrine, pseudoephedrine, amphetamines).Also report the use of drugs that might increase seizure risk when combined with cocaine such as isoniazid (INH), phenothiazines (e.g., thioridazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline), among others. Consult your doctor or pharmacist for details.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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