Patient Comments: C. Difficile - Antibiotics that cause it

Did antibiotics cause your C. difficile colitis? Which one(s) did you take?

Comment from: JustJane, 55-64 Female (Patient) Published: November 03

I was on levofloxacin, for a severe sinus infection. I had two 10 day protocols before a surgery to implant a pain pump. The day I entered the hospital for surgery I realized, when I was weighed, I had lost 9 lb. in the 10 days before surgery. I had surgery on a Thursday and on Saturday I started having diarrhea. I was given Keflex for 5 days following surgery by my surgeon and was only diagnosed with C. difficile colitis 2 weeks later. My primary care physician put me on Flagyl for 10 days and there is no change. He gave me an additional 5 days and still no change.

Was this comment helpful?Yes
Comment from: Mary8479, 25-34 Female (Patient) Published: October 22

I had been on Septra, Cipro, Macrobid, etc., for chronic urinary tract infections. My urologist put me on Keflex for 3 months. Six days later I get C. difficile colitis.

Was this comment helpful?Yes
Comment from: redifrech, 65-74 Male (Patient) Published: October 06

I took clindamycin for a small infection and later was diagnosed with Clostridium difficile. Two weeks after finishing the medication I experienced intestinal cramping, diarrhea and large gobs of mucus. Prior to the use of clindamycin I was basically a very healthy person and now will be struggling to regain my normal life back. I would advise anyone to use caution and look for alternatives before using this drug.

Was this comment helpful?Yes
Comment from: Butterfly Gal, 55-64 Female (Patient) Published: May 05

I took 4 clindamycin tablets before a tooth extraction. One week later I had C. difficile colitis starting with mucus discharge, 2 weeks later blood, and 2 1/2 weeks later diarrhea.

Was this comment helpful?Yes
Comment from: scmama24, 35-44 Female (Patient) Published: March 19

I just was diagnosed with C. difficile colitis today. I was taking cephalexin for an upper respiratory infection.

Was this comment helpful?Yes
Comment from: sa, 19-24 Male (Patient) Published: January 16

I took co-amoxiclav and clindamycin last summer so I think these antibiotics caused my C. difficile colitis.

Was this comment helpful?Yes
Comment from: willneverbethesame, 19-24 Female (Patient) Published: December 17

I had my wisdom teeth out in September, like most young people my age. I was prescribed clindamycin, which I only took for three days. Not only did I develop a dry socket, I found out that was the least of my worries. A month later (thanks to a very respected, determined, and wonderful doctor) after numerous tests, I found out that I had C. difficile colitis. I not warned about this. The oral surgeon could have easily told me to take probiotics and eat yogurt while taking that antibiotic. I had no idea this could turn into such a nightmare. It is Christmas in a few days and all these medical bills are piling up and I am so frustrated to see how many people this has happened to. I should have researched this! It is crazy that the prescription bottle doesn't say take probiotics or eat live cultured yogurt. This needs to be addressed! I need to contact my oral surgeon and tell them they need to spread awareness. Was my chances better not taking it? I think so! Flagyl didn't work for me. I had an IV form round of vancomycin that finally helped. So much for saving for a house.

Was this comment helpful?Yes
Comment from: YYY, 19-24 Female (Patient) Published: December 01

Same as many, clindamycin for a wisdom tooth extraction that ended up being dry socket, caused my C difficile. I have been suffering for a year with on and off constipation and diarrhea. I started having blood in stool and white spots in stool. Finally I went to the doctor and tested feces. Oral surgeons need to stop prescribing this medication. Now I am on metronidazole. Hope it works. Don't take clindamycin!

Was this comment helpful?Yes

Patient Comments

Viewers share their comments

C. Difficile - Diagnosis Question: How was your clostridium difficile colitis diagnosed?
C. Difficile - Share Your Experience Question: Please share your experience with C. difficile colitis.
C. Difficile - Symptoms Question: What were your symptoms associated with C. difficile colitis?
C. Difficile - Treatment Question: What kinds of treatment, including medication, did you receive for C. difficile colitis?

Patient Comments are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified health provider because of something you have read on MedicineNet. The opinions expressed in the comments section are of the author and the author alone. MedicineNet does not endorse any specific product, service or treatment.

Alert If you think you have a medical emergency, call your doctor or 911 immediately.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.