Patient Comments: C. Difficile - Antibiotics that cause it

Did antibiotics cause your C. difficile colitis? Which one(s) did you take?

Comment from: thebarkers0218, 35-44 Female (Patient) Published: November 29

I took clindamycin antibiotic and that was the worst thing I could have ever have took for a bad tooth. It caused C. difficile colitis, explosive diarrhea, high fever and severe abdominal pain. Since having C. difficile colitis, well, I never got well again. I kept having explosive diarrhea, abdominal pain and 10 years later, finally after being treated like I was some kind of hypochondriac, they diagnosed me with ulcerative colitis. Now I pass lots of blood in stool and all thanks to clindamycin antibiotic. Nobody could ever tell me it was not the clindamycin that caused it, I have 10 years of doctor's reports to prove it. Stay away from this antibiotic if you want to stay healthy.

Was this comment helpful?Yes
Comment from: JustJane, 55-64 Female (Patient) Published: November 03

I was on levofloxacin, for a severe sinus infection. I had two 10 day protocols before a surgery to implant a pain pump. The day I entered the hospital for surgery I realized, when I was weighed, I had lost 9 lb. in the 10 days before surgery. I had surgery on a Thursday and on Saturday I started having diarrhea. I was given Keflex for 5 days following surgery by my surgeon and was only diagnosed with C. difficile colitis 2 weeks later. My primary care physician put me on Flagyl for 10 days and there is no change. He gave me an additional 5 days and still no change.

Was this comment helpful?Yes
Comment from: Mary8479, 25-34 Female (Patient) Published: October 22

I had been on Septra, Cipro, Macrobid, etc., for chronic urinary tract infections. My urologist put me on Keflex for 3 months. Six days later I get C. difficile colitis.

Was this comment helpful?Yes
Comment from: redifrech, 65-74 Male (Patient) Published: October 06

I took clindamycin for a small infection and later was diagnosed with Clostridium difficile. Two weeks after finishing the medication I experienced intestinal cramping, diarrhea and large gobs of mucus. Prior to the use of clindamycin I was basically a very healthy person and now will be struggling to regain my normal life back. I would advise anyone to use caution and look for alternatives before using this drug.

Was this comment helpful?Yes
Comment from: Butterfly Gal, 55-64 Female (Patient) Published: May 05

I took 4 clindamycin tablets before a tooth extraction. One week later I had C. difficile colitis starting with mucus discharge, 2 weeks later blood, and 2 1/2 weeks later diarrhea.

Was this comment helpful?Yes
Comment from: hurt by meds, 65-74 Female (Patient) Published: April 06

I am not sure if I have C. difficile colitis yet. I had facial cellulitis 8 to 11 days ago. The emergency room doctor took no blood samples and gave me no IV, just 2 prescriptions; clindamycin (300 mg capsules 4 times a day) and generic Bactrim (800 - 160 tablet 2 times day). I have felt terrible with headache, overall nausea, a rash all over that itches and am now worried.

Was this comment helpful?Yes

Patient Comments

Viewers share their comments

C. Difficile - Diagnosis Question: How was your clostridium difficile colitis diagnosed?
C. Difficile - Share Your Experience Question: Please share your experience with C. difficile colitis.
C. Difficile - Symptoms Question: What were your symptoms associated with C. difficile colitis?
C. Difficile - Treatment Question: What kinds of treatment, including medication, did you receive for C. difficile colitis?

Patient Comments are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified health provider because of something you have read on MedicineNet. The opinions expressed in the comments section are of the author and the author alone. MedicineNet does not endorse any specific product, service or treatment.

Alert If you think you have a medical emergency, call your doctor or 911 immediately.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Health Solutions From Our Sponsors