clonidine, Catapres, Catapres-TTS, Kapvay (cont.)

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Medical and Pharmacy Editor:

Most of these effects subside with prolonged therapy or if doses are reduced. Skin reactions including redness, itching, and darkening of skin, may occur with clonidine patches.

Sexual dysfunction including impotence, decreased sexual desire, and ejaculatory dysfunction, have been reported with clonidine therapy. Such reactions also have been reported with other medications used to treat hypertension.

Severe rebound high blood pressure can occur following withdrawal from clonidine. This reaction is more likely to occur if clonidine is stopped suddenly (without a gradual dose reduction).

Such symptoms can include:

Slowly reducing the dose of clonidine over several days will prevent these symptoms.


GENERIC AVAILABLE: Yes (tablets), No (patches).

PREPARATIONS: Tablets: 0.1, 0.2, and 0.3 mg. Transdermal patches: 0.1, 0.2, and 0.3 mg delivered over 24 hours.

STORAGE: Tablets and patches should be kept at room temperature, 15-30 C (59-86 F).

PRESCRIBED FOR: Clonidine is approved for the treatment of high blood pressure. Non-FDA approved (off-label) uses include treatment of symptoms of narcotic withdrawal, nicotine withdrawal, diabetes-associated diarrhea, diabetic neuropathy (nerve damage), hot flashes associated with menopause, and as an adjunct to manage severe cancer-related pain.

Medically Reviewed by a Doctor on 2/25/2015

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