clonidine, Catapres, Catapres-TTS (cont.)

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Medical and Pharmacy Editor:


Possible serious side effects include:

  • Severe rebound high blood pressure
  • Severe low blood pressure
  • Slow heart rate
  • Withdrawal symptoms
  • Depression

Severe rebound high blood pressure can occur following withdrawal from clonidine. This reaction is more likely to occur if clonidine is stopped suddenly (without a gradual dose reduction).

Such symptoms can include:

Slowly reducing the dose of clonidine over several days will prevent these symptoms.

Medically Reviewed by a Doctor on 5/31/2016

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