clonidine, Catapres, Catapres-TTS, Kapvay (cont.)

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Medical and Pharmacy Editor:

Sexual dysfunction including impotence, decreased sexual desire, and ejaculatory dysfunction, have been reported with clonidine therapy. Such reactions also have been reported with other medications used to treat hypertension.

Severe rebound high blood pressure can occur following withdrawal from clonidine. This reaction is more likely to occur if clonidine is stopped suddenly (without a gradual dose reduction).

Such symptoms can include:

Slowly reducing the dose of clonidine over several days will prevent these symptoms.


GENERIC AVAILABLE: Yes (tablets), No (patches).

PREPARATIONS: Tablets: 0.1, 0.2, and 0.3 mg. Transdermal patches: 0.1, 0.2, and 0.3 mg delivered over 24 hours.

STORAGE: Tablets and patches should be kept at room temperature, 15-30 C (59-86 F).

PRESCRIBED FOR: Clonidine is approved for the treatment of high blood pressure. Non-FDA approved (off-label) uses include treatment of symptoms of narcotic withdrawal, nicotine withdrawal, diabetes-associated diarrhea, diabetic neuropathy (nerve damage), hot flashes associated with menopause, and as an adjunct to manage severe cancer-related pain.

DOSING: The usual oral adult dose is 0.1–0.3 mg twice daily. The maximum oral dose is 2.4 mg daily. Patches should be applied to an area of hairless skin on the upper arm or torso, once every 7 days. When applying a new patch, a different area of skin should be used.

Medically Reviewed by a Doctor on 2/25/2015

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