SIDE EFFECTS: Dizziness, lightheadedness, drowsiness, dry mouth, unusual tiredness, or headache may occur as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute. If you notice mild skin redness or itching around the patch area before finishing the full 7 days of use, remove the patch and replace it with a new one on a new skin site. These effects seem to occur more frequently in patients who use the overlay cover. If the symptoms persist or worsen into a rash, consult your doctor promptly for further instructions to see if you need to remove the patch. Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/slow/irregular heartbeat, depression. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: severe or persistent rash, severe or persistent itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking clonidine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. The patch should be removed before you have certain procedures (e.g., cardioversion, defibrillation) to correct heart conduction disorders. Consult your doctor for more information. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, heart disease (e.g., severe coronary insufficiency, conduction disorders, recent heart attack), depression, blood circulation disorders (e.g., Raynaud's disease). Before having surgery, tell your doctor or dentist that you are taking this medication. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Consult your doctor before breast-feeding.