clonazepam, Klonopin (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects associated with clonazepam are sedation, which is reported in approximately half of patients. Dizziness is reported in one-third of patients.

Other side effects include:

Like all benzodiazepines, clonazepam can cause physical dependence. Suddenly stopping therapy after a few months of daily therapy may be associated with a feeling of loss of self-worth, agitation, and insomnia. If clonazepam is taken continuously for longer than a few months, stopping therapy suddenly may produce seizures, tremors, muscle cramping, vomiting, and/or sweating. Therefore, discontinuation usually is accomplished by reducing the dose gradually.

Antiepileptic medications have been associated with an increased risk of suicidal thinking and behavior. Anyone considering the use of antiepileptic drugs must balance this risk of suicide with the clinical need for the antiepileptic drug. Patients who begin antiepileptic therapy should be closely observed for clinical worsening, suicidal thoughts or unusual changes in behavior.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 0.5, 1, and 2 mg; disintegrating tablets: 0.125, 0.25, 0.5, 1, and 2 mg.

STORAGE: Tablets should be kept at room temperature, between 15 C and 30 C (59 F and 86 F).

DOSING: The dose of clonazepam is tailored to the patient's needs.

  • For seizures in adults the initial dose is 1.5 mg daily in 3 divided doses.
  • Dosage may be increased by 0.5 to 1 mg daily every 3 days until seizures are controlled or side effects preclude further increases in dose.
  • The maximum dose is 20 mg daily. The initial dose for panic disorders is 0.25 mg twice daily.
  • The dose may be increased to the target dose of 1 mg daily after 3 days.
Medically Reviewed by a Doctor on 2/24/2015


Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index