clomiphene, Clomid

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GENERIC NAME: Clomiphene

BRAND NAME: Clomid

DRUG CLASS AND MECHANISM: Clomiphene is an oral medication used for stimulating ovulation. It binds to estrogen receptors in the hypothalamus, pituitary gland, ovary, endometrium, vagina, and cervix. It causes production of hormones (gonadotropins) by the pituitary which stimulates ovulation. The FDA approved clomiphene in February 1967.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 50 mg

STORAGE: Tablets should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Clomiphene is used for stimulating ovulation in women with ovulatory dysfunction who are not pregnant, do not have ovarian cysts or abnormal bleeding, and have normal liver function.

DOSING: The recommended dose is 50 to 100 mg orally for 5 days. The initial dose is 50 mg which may be increased to 100 mg if there is no response. Dosage may be repeated as early as 30 days after the previous treatment.

DRUG INTERACTIONS: No drug interactions are listed in the prescribing information.

PREGNANCY: Clomiphene should not be taken by pregnant women since it does not offer any benefit to pregnant women.

NURSING MOTHERS: It is not known whether clomiphene is excreted into breast milk. It may reduce lactation in some women.

SIDE EFFECTS: The most common side effects of clomiphene are ovarian enlargement, flushing, stomach discomfort, breast discomfort, blurred vision, nausea, and vomiting. Other side effects include abnormal heart beats, acne, allergic reactions, headaches, uterine bleeding, back pain, and muscle pain.

REFERENCE: FDA Prescribing Information


Medically Reviewed by a Doctor on 9/6/2013



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