clindamycin phosphate vaginal cream, Cleocin, Clindesse (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: Yes
PREPARATIONS: Cream: 2%
STORAGE: Clindamycin should be stored at room temperature 20 C to 25 C (68 F to 77 F).
DOSING: The recommended dose is one full applicator of clindamycin phosphate vaginal cream 2% intravaginally, preferably at bedtime, for 3 or 7 days in non-pregnant women and for 7 days in pregnant women.
DRUG INTERACTIONS: Clindamycin give orally may act as a neuromuscular blocker. This means that it can increase the action of neuromuscular blocking drugs (for example, pancuronium and vecuronium). However, very little clindamycin is absorbed into the blood stream when given vaginally so the likelihood of drug interactions is less.
PREGNANCY: The frequency of congenital abnormalities was not increased when pregnant women used clindamycin during the second and third trimesters, and clindamycin vaginal cream is approved for use during the second and third trimesters of pregnancy. Clindamycin should not be used during the first trimester of pregnancy unless it is clearly needed because it has not been properly evaluated during the first trimester.
NURSING MOTHERS: Oral clindamycin is excreted in breast milk and should not be used by nursing mothers, or nursing should be stopped. It is not known whether clindamycin given vaginally is excreted in breast milk.
Medically reviewed by Eni Williams, PharmD
REFERENCE: FDA Prescribing Information.
Medically Reviewed by a Doctor on 2/25/2015
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