GENERIC NAME: clindamycin and benzoyl peroxide gel
BRAND NAME: Benzaclin, Acanya, Duac, Onexton
DRUG CLASS AND MECHANISM: Clindamycin/benzoyl peroxide is a combination of an antibiotic, clindamycin, and benzoyl peroxide, another drug that has antibacterial effects. Clindamycin/benzoyl peroxide is used topically (applied to the skin) for the treatment of pimples (acne). Both agents are active against Propionibacterium acnes, a bacterium which has been associated with acne. Clindamycin probably reduces acne by penetrating into the skin and killing bacteria that contribute to the formation of acne. Benzoyl peroxide works through several mechanisms. It kills the bacteria and promotes the growth of new skin cells. It also dries the skin. Increased cell growth leads to replacement of the pimples with new skin. Combaining clindamycin and benzoyl peroxide is more convenient than using them separately. The FDA approved clindamycin/benzoyl peroxide in December 2000.
PRESCRIBED FOR: Clindamycin/benzoyl peroxide is used for the treatment of acne.
SIDE EFFECTS: The most common side effect of clindamycin/benzoyl peroxide are:
Allergic reactions may also occur. Diarrhea, sometimes bloody, has been reported with topical clindamycin. This reaction, although quite rare, can be dangerous. Discontinuation is recommended if marked diarrhea develops.
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