clindamycin and benzoyl peroxide gel, Benzaclin, Acanya, Duac

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GENERIC NAME: clindamycin and benzoyl peroxide gel

BRAND NAME: Benzaclin, Acanya, Duac

DRUG CLASS AND MECHANISM: Clindamycin/benzoyl peroxide is a combination of an antibiotic, clindamycin, and benzoyl peroxide, another drug that has antibacterial effects. Clindamycin/benzoyl peroxide is used topically (applied to the skin) for the treatment of pimples (acne). Both agents are active against Propionibacterium acnes, a bacterium which has been associated with acne. Clindamycin probably reduces acne by penetrating into the skin and killing bacteria that contribute to the formation of acne. Benzoyl peroxide works through several mechanisms. It kills the bacteria and promotes the growth of new skin cells. It also dries the skin. Increased cell growth leads to replacement of the pimples with new skin. Combining clindamycin and benzoyl peroxide is more convenient than using them separately. The FDA approved clindamycin/benzoyl peroxide in December 2000.



PREPARATIONS: Gel (clindamycin/benzoyl peroxide): 1%/ 5% or 1.2%/2.5%

STORAGE: The gel can be stored at room temperature, up to 25 C (77 F), for up to three months after it is dispensed by the pharmacy. Unused gel should be discarded after three months.

PRESCRIBED FOR: Clindamycin/benzoyl peroxide is used for the treatment of acne.

DOSING: Clindamycin/benzoyl peroxide should be applied to acne lesions at bedtime (Duac), once daily (Acanya), twice daily, morning and evening (Benzaclin), or as directed by a physician. Affected areas should be washed, rinsed with warm water, and patted dry before applying clindamycin/benzoyl peroxide.

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