Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Clindamycin given orally may act as a neuromuscular blocker. This means it
can increase the action of neuromuscular blocking drugs (for example,
pancuronium and vecuronium). Less clindamycin is absorbed into the blood stream
when given as a suppository so the likelihood of an interaction with these drugs
is less likely.
PREGNANCY AND BREASTFEEDING SAFETY:
The frequency of congenital abnormalities was not increased when pregnant
women used oral clindamycin during the second and
Pregnant women who used clindamycin vaginal cream during the
reported abnormal labor more frequently than those who received placebo.
Clindamycin vaginal suppositories have not been properly evaluated during the
first trimester of pregnancy. They should only be used during the first
trimester of pregnancy when they are clearly needed.
Oral clindamycin is excreted in breast milk and should not be used by
mothers or nursing should be stopped.
It is not known whether clindamycin from vaginal suppositories is excreted in