clindamycin vaginal suppository (Cleocin)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

19 Habits That Wreck Your Teeth

DOSING:

  • Insert 1 suppository into the vagina at night for 3 days.
  • Patients should avoid vaginal intercourse or vaginal products (such as tampons or douches) during treatment with clindamycin vaginal suppositories.

DRUG INTERACTIONS:

  • Clindamycin given orally may act as a neuromuscular blocker. This means it can increase the action of neuromuscular blocking drugs (for example, pancuronium and vecuronium). Less clindamycin is absorbed into the blood stream when given as a suppository so the likelihood of an interaction with these drugs is less likely.

PREGNANCY AND BREASTFEEDING SAFETY:

  • The frequency of congenital abnormalities was not increased when pregnant women used oral clindamycin during the second and third trimesters.
  • Pregnant women who used clindamycin vaginal cream during the second trimester reported abnormal labor more frequently than those who received placebo.
  • Clindamycin vaginal suppositories have not been properly evaluated during the first trimester of pregnancy. They should only be used during the first trimester of pregnancy when they are clearly needed.
  • Oral clindamycin is excreted in breast milk and should not be used by nursing mothers or nursing should be stopped.
  • It is not known whether clindamycin from vaginal suppositories is excreted in breast milk.
Medically Reviewed by a Doctor on 12/31/2015
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