clindamycin, oral (Cleocin) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects of clindamycin are:

It also frequently causes:

Clindamycin causes Clostridium difficile associated diarrhea (CDAD) because it can alter the normal bacteria in the colon and encourage overgrowth Clostridium difficile, a bacteria which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting clindamycin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.



PREPARATIONS: Capsule: 75, 150, and 300 mg. Oral Solution: 75 mg/5 ml

STORAGE: Clindamycin should be store at room temperature, 20 C to 25 C (68 to 77 F).

DOSING: The recommended dose for adults for serious infections is 150 to 450 mg every 6 to 8 hours up to a maximum dose of 1.8 grams per day. For pediatric patients the recommended dose is 8 to 20 mg/kg/day divided into 3 or 4 equal doses.

To avoid throat irritation, clindamycin should be taken with a full glass of water.

DRUG INTERACTIONS: Clindamycin may act as a neuromuscular blocker. This means it can increase the action of neuromuscular blocking drugs (for example, pancuronium and vecuronium), which are used during surgery.

Medically Reviewed by a Doctor on 2/20/2015

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