clarithromycin, Biaxin, Biaxin XL (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Clarithromycin increases blood levels of sildenafil (Viagra, Revatio), tadalafil (Cialis, Adcirca), vardenafil (Levitra), theophylline and carbamazepine (Tegretol), thereby increasing side effects of these drugs.

Ritonavir (Norvir) and atazanavir (Reyataz) increase blood levels of clarithromycin while efavirenz (Sustiva), nevirapine (Viramune), rifampin, decrease blood levels of clarithromycin.

Itraconazole (Sporanox) and saquinavir (Invirase) may increase blood levels of clarithromycin while clarithromycin increases blood levels or both drugs.

The occurrence of abnormal heart beats may increase when clarithromycin is combined with drugs that affect heart beat (for example, amiodarone [Coradone], quinidine [Quinidine Gluconate, Quinidine Sulfate], and disopyramide).

PREGNANCY: Safe use of clarithromycin in pregnancy has not been established. There are no adequate studies in pregnant women.

NURSING MOTHERS: Clarithromycin is excreted in breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 12/30/2014

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