clarithromycin, Biaxin, Biaxin XL

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: clarithromycin

BRAND NAME: Biaxin, Biaxin XL

DRUG CLASS AND MECHANISM: Clarithromycin is a semi-synthetic macrolide antibiotic chemically related to erythromycin and azithromycin (Zithromax). It is effective against a wide variety of bacteria, such as Haemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Staphylococcus aureus, and mycobacterium avium, and many others. Like all macrolide antibiotics, clarithromycin prevents bacteria from growing by interfering with their ability to make proteins. Due to the differences in the way proteins are made in bacteria and humans, the macrolide antibiotics do not interfere with production of proteins in humans. The FDA approved clarithromycin in October 1991.

PRESCRIBED FOR: Clarithromycin is effective against susceptible bacteria causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia, and skin infections. It also is used in treating infections caused by mycobacterium avium, a bacterium closely related to the bacterium that causes tuberculosis. Clarithromycin has been used in combination with omeprazole/sodium bicarbonate (Prilosec) in treating H. Pylori that causes stomach ulcers.

Medically Reviewed by a Doctor on 12/30/2014

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