CISAPRIDE-ORAL, Propulsid (cont.)

DRUG INTERACTIONS: Tell your doctor of all the prescription and nonprescription drugs you use, especially of: blood thinners such as warfarin, anticholinergics such as dicyclomine, anti-anxiety drugs, tranquilizers, sedatives, azole antifungals (e.g., ketoconazole, fluconazole), troleandomycin, erythromycin, clarithromycin, certain protease inhibitors (e.g., ritonavir, indinavir), nefazodone, cimetidine, mibefradil, terodiline, certain diuretics/"water pills" (e.g., furosemide), fluvoxamine, certain tetracyclic antidepressants (e.g., maprotiline). Report other drugs which affect the heart rhythm (QTc prolongation), such as: quinidine, procainamide, sotalol, pimozide, amiodarone. Ask your doctor or pharmacist for more details. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include diarrhea, stomach cramping, trouble sleeping, seizures, or irregular heartbeat.

NOTES: Talk to your health care provider about dietary changes and raising the head of your bed which may help relieve heartburn. Certain tests (such as EKG and electrolytes) may be done as part of drug monitoring before and during therapy.

MISSED DOSE: If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.

Last Editorial Review: 3/2/2005

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