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February 10, 2012
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CISAPRIDE-ORAL, Propulsid (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: intestinal or stomach disorders, bleeding ulcers, lung problems, kidney problems, liver disease, heart problems (e.g., QT prolongation), cancer, certain blood disorders that may be caused by sudden loss of water (electrolyte disorders such as hypokalemia, hypocalcemia, hypomagnesemia), vomiting, poor diet, eating disorders (e.g., anorexia or bulimia), allergies (especially drug allergies). Limit alcohol intake as it may aggravate drug side effects. Caution is advised when using this drug in children less than 16 years of age because they may be more sensitive to the effects of the drug. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all the prescription and nonprescription drugs you use, especially of: blood thinners such as warfarin, anticholinergics such as dicyclomine, anti-anxiety drugs, tranquilizers, sedatives, azole antifungals (e.g., ketoconazole, fluconazole), troleandomycin, erythromycin, clarithromycin, certain protease inhibitors (e.g., ritonavir, indinavir), nefazodone, cimetidine, mibefradil, terodiline, certain diuretics/"water pills" (e.g., furosemide), fluvoxamine, certain tetracyclic antidepressants (e.g., maprotiline). Report other drugs which affect the heart rhythm (QTc prolongation), such as: quinidine, procainamide, sotalol, pimozide, amiodarone. Ask your doctor or pharmacist for more details. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.



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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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