- Cirrhosis is a complication of liver disease which involves loss of liver cells and irreversible scarring of the liver.
- Alcohol and viral hepatitis B and C are common causes of cirrhosis, although there are many other causes.
- Cirrhosis can cause weakness, loss of appetite, easy bruising, yellowing of the skin (jaundice), itching, and fatigue.
- Diagnosis of cirrhosis can be suggested by history, physical examination and blood tests, and can be confirmed by liver biopsy.
- Complications of cirrhosis include edema and ascites, spontaneous bacterial peritonitis, bleeding from varices, hepatic encephalopathy, hepatorenal syndrome, hepatopulmonary syndrome, hypersplenism, and liver cancer.
- Treatment of cirrhosis is designed to prevent further damage to the liver, treat complications of cirrhosis, and preventing or detecting liver cancer early.
- Transplantation of the liver is becoming an important option for treating patients with advanced cirrhosis.
Reviewed on 3/5/2014
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