cimetidine, Tagamet HB (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: Side effects due to cimetidine are rare and generally reversible once the medication is stopped. Minor side effects include:

Major side effects include confusion and hallucinations (usually in elderly or critically ill patients), enlargement of the breasts; impotence (usually seen in patients on high doses for prolonged periods); decreased white blood cell counts.

Other side effects include:

  • irregular heartbeat,
  • rash,
  • visual changes,
  • allergic reactions, and
  • hepatitis.

PRESCRIPTION: Yes and OTC (Heart Burn)

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 200, 300, 400, and 800 mg. Liquid: 300 mg/5 ml. Injection: 150 mg/ml.

STORAGE: Store at room temperature 15 C to 30 C (59 F to 86 F).

DOSING:

Duodenal ulcers are treated with 800 to 1600 mg at bedtime or 300 mg 4 times a day at meal times and bedtime, or 400 mg twice a day for 4-6 weeks. Maintenance therapy is 400 mg at bedtime.

Active gastric ulcers are treated with 800 mg at bedtime or 300 mg 4 times a day at meal times and bedtime for up to 8 weeks.

The regimen for GERD is 800 mg twice a day or 400 mg 4 times a day for 12 weeks.

Pathological hypersecretory conditions are treated with 300 mg 4 times daily up to 2400 mg daily.

Heartburn, indigestion and/or sour stomach may be treated with 200 mg once or twice daily and may be administered up to 30 minutes before ingestion of food or beverages that may cause heartburn.

Medically Reviewed by a Doctor on 4/14/2015


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