cimetidine, Tagamet (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Because cimetidine reduces stomach acid, it may reduce the absorption of drugs (for example, ketoconazole [Nizoral, Extina, Xolegel, Kuric]) that are best absorbed in acidic conditions. Such drugs should be administered at least 2 hours before the administration of cimetidine.

PREGNANCY: There are no adequate studies of cimetidine in pregnant women.

NURSING MOTHERS: Cimetidine is excreted in breast milk.

SIDE EFFECTS: Side effects due to cimetidine are rare and generally reversible once the medication is stopped. Minor side effects include constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. Major side effects include confusion and hallucinations (usually in elderly or critically ill patients), enlargement of the breasts; impotence (usually seen in patients on high doses for prolonged periods); decreased white blood cell counts. Other side effects include irregular heartbeat, rash, visual changes, allergic reactions, and hepatitis.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 6/13/2014

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