ciclopirox, Penlac, Loprox
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: ciclopirox
BRAND NAME: Penlac, Loprox
DRUG CLASS AND MECHANISM: Ciclopirox is a synthetic broad-spectrum antifungal agent that inhibits the growth of dermatophytes, a type of fungus that grows on the skin, hair, and nails. When applied to skin a very small percentage is absorbed into the body. It was approved for use in the U.S. by the FDA in December 1999.
GENERIC AVAILABLE: Yes
PREPARATIONS: Solution: 8%; Cream/lotion/gel: 0.77%; Shampoo: 1%
STORAGE: Ciclopirox should be stored at room temperature, 15-30 C (59-86 F). Use or storage near heat or open flame should be avoided since the solution is flammable.
PRESCRIBED FOR: Ciclopirox is used topically (on the skin or nails) for treating mild or moderate finger or toenail fungus (onychomycosis), athlete's foot, ringworm, jock itch, tinea versicolor, and seborrheic dermatitis of the scalp.
DOSING: Ciclopirox is applied once or twice a day to affected areas depending on the condition being treated.
DRUG INTERACTIONS: Use together with other medications for fungal infection is not recommended. Nail polish or other cosmetic products should not be used on the treated nails.
PREGNANCY: There are no adequate studies of ciclopirox in pregnant women.
NURSING MOTHERS: When applied to skin a very small amount of ciclopirox is absorbed into the body. It is not known whether ciclopirox is excreted in breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing ciclopirox to nursing mothers.
Reference: FDA Prescribing Information
Last Editorial Review: 7/19/2012
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