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- Chronic fatigue syndrome (CFS) or systemic exertion intolerance disease (SEID) facts
- What is chronic fatigue syndrome (CFS or SEID)?
- What causes chronic fatigue syndrome or systemic exertional intolerance disease?
- What are risk factors for CFS/SEID?
- What are systemic exertion intolerance disease or chronic fatigue syndrome symptoms and signs?
- What are CFS/SEID symptoms in men?
- What are SEID/CFS symptoms in women?
- How is chronic fatigue syndrome (or systemic exertion intolerance disease) diagnosed?
- What is the treatment for CFS/SEID?
- Is there a cure for CFS/SEID?
- What is the prognosis (outcome) for CFS/SEID?
- Is it possible to prevent CFS/SEID?
- Where can people find additional information about CFS/SEID?
Quick GuideChronic Fatigue Syndrome (CFS) Symptoms, Diagnosis, and Treatment
What is the treatment for CFS/SEID?
There is no known cure for CFS/SEID chronic fatigue syndrome; treatment is based on those therapies that reduce the symptoms. In general, patients who are diagnosed within the first two years of symptoms respond better to symptomatic treatment than those patients diagnosed after two or more years of having the disease. Treatments to reduce symptoms are individualized for each patient as no single therapy helps all CFS/SEID patients.
Drug therapies (bupropion [Wellbutrin], sertraline [Zoloft], and other antidepressant drugs) are used to treat symptoms of sleep, pain, and psychological problems. Some have used Adderall (off-label use). Other therapies that are used include stress reduction and lifestyle changes (which may include diet and exercise reduction). Some investigators suggest diet and nutrition play a role and recommend vitamin D, B6, B12, lysine, and glutathione supplements while others do not. Some clinicians may prescribe antibiotics such as metronidazole (Flagyl) or amoxicillin and clavulanic acid (Augmentin) if the patient has high levels of antibodies that react with C. pneumoniae or other organisms. Other treatments that claim some positive effects on CFS symptoms include holistic treatments such as bananas, maca (a plant root from Peru), pau d'arco (herb from the bark of the taheebo tree in Central America), and spirulina (plankton).
Acupuncture and fluorescent-light treatments also are claimed to help CFS patients. Most of these other therapies have not been well studied by experts who treat CFS.
Most clinicians agree that patients with CFS need a team approach to their illness. The most disruptive symptoms should be addressed first. In general, the therapy will be a combination of psychological counseling (to help with the day-to-day burden CFS imposes on the patient's life) and mild guided exercise (a physical therapist might be able to help; care should be taken to not be too strenuous). Cognitive-behavioral therapy seems to work well with pediatric-aged patients.