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- Chronic fatigue syndrome (CFS) or systemic exertion intolerance disease (SEID) facts
- What is chronic fatigue syndrome (CFS or SEID)?
- What causes chronic fatigue syndrome or systemic exertional intolerance disease?
- What are risk factors for CFS/SEID?
- What are systemic exertion intolerance disease or chronic fatigue syndrome symptoms and signs?
- What are CFS/SEID symptoms in men?
- What are SEID/CFS symptoms in women?
- How is chronic fatigue syndrome (or systemic exertion intolerance disease) diagnosed?
- What is the treatment for CFS/SEID?
- Is there a cure for CFS/SEID?
- What is the prognosis (outcome) for CFS/SEID?
- Is it possible to prevent CFS/SEID?
- Where can people find additional information about CFS/SEID?
Quick GuideChronic Fatigue Syndrome (CFS) Symptoms, Diagnosis, and Treatment
What are risk factors for CFS/SEID?
Without knowing the cause of CFS/SEID, it is difficult to determine risk factors. However, statistics gathered about people with diagnosed CFS/SEID do tell something about some high-risk groups. For example, although people of every age, gender, race, and economic group can get CFS/SEID, it is most commonly diagnosed in people in the 40- and 50-year-old age group. In addition, CFS/SEID is diagnosed about four times as often in women (some investigators consider menopause as a possible risk factor). In the pediatric-aged group, teens are most often affected.
What are systemic exertion intolerance disease or chronic fatigue syndrome symptoms and signs?
The symptoms and signs of CFS/SEID are complex but specific. The patient must have severe chronic fatigue of six months or longer duration with other known medical conditions excluded by clinical diagnosis. In addition, the patients have four or more of the following symptoms that either occurred at the same time or after the severe chronic fatigue. The symptoms are substantial impairment in short-term memory or concentration; sore throat; tender lymph nodes; muscle pain; multi-joint pain without swelling or redness; headaches of a new type, pattern, or severity; unrefreshing sleep; and post-exertion malaise lasting more than 24 hours. Patients may often have additional symptoms such as double vision, mild fevers, earaches, diarrhea, and many other symptoms, but they do not fit into the criteria that are considered to be part of the definition of CFS.
The following are five main symptoms that the new IOM considers key for SEID or CFS:
- Reduction or impairment in ability to carry out normal daily activities, accompanied by profound fatigue
- Post-exertional malaise (worsening of symptoms after physical, cognitive, or emotional effort)
- Unrefreshing sleep
- Cognitive impairment
- Orthostatic intolerance (symptoms that worsen when a person stands upright and improve when the person lies back down)