choline magnesium salicylate, Trilisate

  • Pharmacy Author:
    Annette (Gbemudu) Ogbru, PharmD, MBA

    Dr. Gbemudu received her B.S. in Biochemistry from Nova Southeastern University, her PharmD degree from University of Maryland, and MBA degree from University of Baltimore. She completed a one year post-doctoral fellowship with Rutgers University and Bristol Myers Squibb.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What is choline magnesium salicylate, and how does it work (mechanism of action)?

Choline magnesium salicylate (or trisalicylate) is a type of nonsteroidal anti-inflammatory drug (NSAID), referred to as a salicylate, which is effective in treating fever, pain, and inflammation in the body. Other drugs within the same class are aspirin, diflunisal (Dolobid) and salsalate (Disalcid). They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. The salicylates block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

What brand names are available for choline magnesium salicylate?

Trilisate (Please Note: This brand name drug is no longer available in the US)

Is choline magnesium salicylate available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for choline magnesium salicylate?

Yes

What are the side effects of choline magnesium salicylate?

Common side effects of choline magnesium salicylate are heartburn, stomach ulcers, nausea, or vomiting. Patients should tell their doctor immediately if any of these unusual but potentially serious side effects occur: severe abdominal pain, easy bruising or bleeding, fast heartbeat, persistent nausea or vomiting, unusual tiredness, change in the amount or color of urine, yellowing of the eyes or skin, unusual bleeding, and hearing loss.

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