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High doses are more likely to cause side effects such as sweating, a fishy body odor, gastrointestinal distress, diarrhea, and vomiting.
There is some concern that increasing dietary choline intake might increase the risk of colorectal cancer. One study found that women eating a diet that contains a lot of choline have an increased the risk of colon cancer. However, more research is still needed to determine the effects of diet on colon cancer.
Daily Upper Intake Levels (UL, the highest level of intake that is not likely to cause harm) for choline are: 1 gram daily for children 1-8 years, 2 grams for children 9-13 years, 3 grams for children 14-18 years, and 3.5 grams for adults over 18 years of age.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.