chlorpheniramine, pseudoephedrine, Deconamine (Discontinued) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Other important side effects of pseudoephedrine include stimulation of the nervous system leading to:

PRESCRIBED FOR: The combination drug was used for the temporary relief of runny nose, sneezing, nasal congestion from the common cold. Deconamine also was used for inflamed nasal passages (sinusitis), hay fever (allergic rhinitis) and sinus congestion.

PRESCRIPTION: No

GENERIC AVAILABLE: No

PREPARATIONS: Tablets of 4 mg chlorpheniramine/60 mg pseudoephedrine; chew tabs of 1 mg c/15 mg p; syrup of 2 mg c/30 mg p.

STORAGE: Combinations of chlorpheniramine and pseudoephedrine should be stored at room temperature in an air-tight container.

DOSING: The combination drug may be taken with or without food. It must be used cautiously in patients with heart (coronary artery) disease and angina, diabetes, lung diseases, especially asthma, glaucoma, and narrowing of the stomach exit (pyloric stenosis).

DRUG INTERACTIONS: The combination drug can cause drowsiness and impaired ability to operate machinery. It contains pseudoephedrine which should not be taken with MAO inhibitors drugs. Caution must be exercised in the administration of this drug to patients with heart or lung disease. The combination drug should not be combined with other drugs containing pseudoephedrine (such as Sudafed) because of increased risk of side effects on the heart and blood vessels. While misuse of the combination drug for the purpose of getting "high" is unfamiliar to the editors, it is a specific warning from the manufacturer that patients be aware of possible "additive" effects of the drug when taken with alcohol and other central nervous depressants (such as sedatives and tranquilizers). This means that when the drug is taken with, for example, alcohol, the effect of the alcohol could be magnified. Conversely, alcohol increases the sedating qualities of Deconamine.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information


Medically Reviewed by a Doctor on 5/27/2015


Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index