chlorpheniramine and hydrocodone, Tussionex, TussiCaps, Tussionex Pennkinetic, Vituz (cont.)
Eni Williams, PharmD, PhD
Eni Williams, PharmD, PhD
Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.
Medical and Pharmacy Editor:
Hydrocodone can depress breathing, and should be used with caution in elderly, debilitated patients, and in patients with serious lung disease. Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery. Hydrocodone may be habit forming. Mental and physical dependence can occur but are unlikely when used for short-term relief of pain.
GENERIC AVAILABLE: Yes
PREPARATIONS: Liquid suspension. Each teaspoonful (5 ml) contains chlorpheniramine, 8 mg and hydrocodone, 10 mg.
STORAGE: The suspension should be stored at room temperature, between 15-30 C (59-86 F).
DOSING: The usual dose is 2.5 ml (1/2 teaspoon) to 5 ml (1 teaspoonful) twice daily. The suspension should be shaken prior to each use.
DRUG INTERACTIONS: Chlorpheniramine (although not generally sedating itself) and hydrocodone both add to the sedating effects of alcohol and other drugs that can cause sedation such as the benzodiazepine class of anti-anxiety drugs (for example, diazepam [Valium], lorazepam [Ativan], clonazepam [Klonopin], alprazolam [Xanax]); the narcotic class of pain medications and its derivatives (for example, oxycodone and acetaminophen [Percocet], hydrocodone/acetaminophen [Vicodin], Dilaudid, codeine, propoxyphene [Darvon]); the tricyclic class of antidepressants (for example, amitriptyline [Elavil, Endep], imipramine [Tofranil], desipramine [Norpramin]); the antipsychotic class of drugs (for example, thioridazine (Mellaril), triflupromazine (Stelazine)]; and certain antihypertensive medications (for example, clonidine [Catapres], propranolol [Inderal]).
Medically Reviewed by a Doctor on 4/6/2015
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