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chloroquine - oral, Aralen (cont.)

DRUG INTERACTIONS: See also How to Use section.The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.Some products that may interact with this drug include: agalsidase, mefloquine, penicillamine, sulfadoxine/pyrimethamine, products that may harm the liver (such as acetaminophen, isoniazid, alcohol).This medication can speed up or slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include cyclosporine and praziquantel among others.Many drugs besides chloroquine may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, mefloquine, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using chloroquine, report all medications you are currently using to your doctor or pharmacist.Cimetidine is a nonprescription drug that is commonly used to treat extra stomach acid. Because cimetidine and other antacids may interact with chloroquine, ask your pharmacist about other products to treat extra stomach acid.Take chloroquine at least 2 hours before or after taking ampicillin. Chloroquine may decrease the amount of ampicillin in your body and the ampicillin may not work as well.Although no longer available in the United States, a certain rabies vaccine (HDCV) may not work as well if given while you are taking chloroquine.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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