chlorhexidine gluconate oral rinse (Peridex, Periogard, Periochip)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: chlorhexidine gluconate
BRAND NAME: Peridex, Periogard, Periochip
DRUG CLASS AND MECHANISM: Chlorhexidine is an antiseptic and antimicrobial oral rinse. It provides protection against a wide range of bacteria. It kills bacteria by binding to bacteria cell walls. The FDA approved chlorhexidine in August 1986.
PRESCRIBED FOR: Chlorhexidine is commonly prescribed orally for treating gingivitis which causes redness, swelling, and bleeding of the gums.
It also is used after rooting and planning procedures for adult periodontitis.
Its safety and efficacy has not been established for patients with acute necrotizing ulcerating gingivitis (ANUG).
SIDE EFFECTS: Side effects of chlorhexidine include:
Cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) have been reported.
GENERIC AVAILABLE: Yes
PREPARATIONS: Chlorhexidine gluconate is available in a 0.12% concentration as an oral rinse solution. Most commonly it is available in a 16 fluid ounce (473 ml) child-resistant dispensing container.
Medically Reviewed by a Doctor on 4/23/2015
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