chlorhexidine gluconate oral rinse (Peridex, Periogard, Periochip)

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Medical and Pharmacy Editor:

GENERIC NAME: chlorhexidine gluconate

BRAND NAME: Peridex, Periogard, Periochip

DRUG CLASS AND MECHANISM: Chlorhexidine is an antiseptic and antimicrobial oral rinse. It provides protection against a wide range of bacteria. It kills bacteria by binding to bacteria cell walls. The FDA approved chlorhexidine in August 1986.

PRESCRIBED FOR: Chlorhexidine is commonly prescribed orally for treating gingivitis which causes redness, swelling, and bleeding of the gums.

It also is used after rooting and planning procedures for adult periodontitis.

Its safety and efficacy has not been established for patients with acute necrotizing ulcerating gingivitis (ANUG).

SIDE EFFECTS: Side effects of chlorhexidine include:

  • staining of the teeth and other oral areas,
  • dental tartar (dental calculus),
  • altered sense of taste,
  • toothache, and
  • oral mucosal irritation.

Cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) have been reported.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Chlorhexidine gluconate is available in a 0.12% concentration as an oral rinse solution. Most commonly it is available in a 16 fluid ounce (473 ml) child-resistant dispensing container.

Medically Reviewed by a Doctor on 4/23/2015



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