chlorhexidine gluconate oral rinse (Peridex, Periogard)

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GENERIC NAME: Chlorhexidine gluconate

BRAND NAME: Peridex; Periogard.

DRUG CLASS AND MECHANISM: Chlorhexidine is an antiseptic and antimicrobial oral rinse. It provides protection against a wide range of bacteria. It kills bacteria by binding to bacteria cell walls. The FDA approved chlorhexidine in August 1986.



PREPARATIONS: Chlorhexidine gluconate is available in a 0.12% concentration as an oral rinse solution. Most commonly it is available in a 16 fluid ounce (473 ml) child-resistant dispensing container.

Other sizes that are available are 0.5 fluid ounce (15 ml) and 4 fluid ounce (118 ml) in a child-resistant dispensing container. A 64 fluid ounce (1893 ml) is available in a pump-dispensing container.

STORAGE: Chlorhexidine gluconate should be store at room temperature between 15 C to 30 C F (59 F to 86 F).

PRESCRIBED FOR: Chlorhexidine is a commonly prescribed orally for treating gingivitis which causes redness, swelling, and bleeding of the gums. Its safety and efficacy has not been established for patients with acute necrotizing ulcerating gingivitis (ANUG).

DOSING AND ADMINISTRATION: Usually the mouth is rinsed with 15 ml (1 Tbsp) of undiluted chlorhexidine twice daily (morning and evening) for 30 seconds after brushing.

Individuals must expectorate the chlorhexidine after rinsing and must not rinse their mouths with water or mouthwashes, brush their teeth, or eat immediately after using chlorhexidine.

Medically Reviewed by a Doctor on 4/16/2014

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