chlordiazepoxide hydrochloride and clidinium bromide (Librax) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: Chlordiazepoxide hydrochloride/clidinium bromide may be taken with or without food. Take 1 to two capsules every 6 to 8 hours before meals and at bedtime.

DRUG INTERACTIONS: Chlordiazepoxide hydrochloride/ clidinium bromide should not be used in people with glaucoma or urinary retention (difficulty urinating) due to benign prostatic hypertrophy (BPH) because clidinium blocks the action of choline, increasing intraocular pressure and causing difficulty urinating. Chlordiazepoxide has sedative effects and should not be combined with alcohol or other central nervous system depressants.

PREGNANCY: Chlordiazepoxide hydrochloride/clidinium bromide is not recommended for use in pregnant women because it increases the risk of congenital malformations during the first trimester.

Nursing Mothers: Nursing Mothers: Chlordiazepoxide hydrochloride/clidinium bromide is present in breast milk and should not be used while breastfeeding.


  • Adverse reactions may include drowsiness, dizziness, and confusion. Nausea, constipation, and dry mouth may occur.
  • Urinary hesitancy or retention are seen, particularly in the elderly.
  • Skin eruptions and liver abnormalities are less common.
  • Avoid driving or operating machinery while taking chlordiazepoxide hydrochloride/clidinium bromide because it reduces mental alertness.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 11/19/2014

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