chlordiazepoxide hydrochloride and clidinium bromide (Librax)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What is chlordiazepoxide hydrochloride, clidinium bromide, and how does it work (mechanism of action)?

Chlordiazepoxide hydrochloride and clidinium bromide (Librax) combines the anti-anxiety action of chlordiazepoxide and the antispasmodic effects of clidinium. It also blocks the acid secretion of the gastrointestinal tract and inhibits the action of nerves that are very active in certain diseases. The FDA classifies the combination as possibly effective as additional therapy for treatment of peptic ulcers, irritable bowel syndrome (IBS), GI spasms and some intestinal infections.

What brand names are available for chlordiazepoxide hydrochloride, clidinium bromide?

Librax

Is chlordiazepoxide hydrochloride, clidinium bromide available as a generic drug?

GENERIC AVAILABLE: yes

Do I need a prescription for chlordiazepoxide hydrochloride, clidinium bromide?

yes

What are the side effects of chlordiazepoxide hydrochloride, clidinium bromide?

  • Adverse reactions may include drowsiness, dizziness, and confusion. Nausea, constipation, and dry mouth may occur.
  • Urinary hesitancy or retention are seen, particularly in the elderly.
  • Skin eruptions and liver abnormalities are less common.
  • Avoid driving or operating machinery while taking chlordiazepoxide hydrochloride/clidinium bromide because it reduces mental alertness.

Quick GuideDigestive Disorders: Common Misconceptions

Digestive Disorders: Common Misconceptions
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