chlordiazepoxide (Librium)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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Additionally, inducers of the CYP 3A4 enzymes may increase the activity of these enzymes and cause blood levels of chlordiazepoxide to decrease.

Examples of CYP 3A4 inducers are:

Chlordiazepoxide has depressant effects on the central nervous system. Medications which have similar activity may increase the risk for drowsiness, respiratory depression, and other CNS depressant effects. Therefore, co-administration with alcohol, kava-kava, other benzodiazepines, and opiates should generally be avoided.

PREGNANCY: Chlordiazepoxide is classified as FDA pregnancy risk category D. Due to the risk of potential harm to the fetus, use of chlordiazepoxide during pregnancy is not recommended.

NURSING MOTHERS: This medication is thought to be excreted into breast milk. Due to the lack of conclusive safety data, use in nursing mothers is not recommended.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 12/22/2014
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