chlordiazepoxide (Librium) (cont.)

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Chlordiazepoxide was initially approved by the US FDA in 1960. The injectable formulation of chlordiazepoxide is no longer available in the US.

PRESCRIBED FOR: Chlordiazepoxide is used for the management of anxiety disorders. It is used to provide short term relief of anxiety symptoms, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Effectiveness and safety of long term use of chlordiazepoxide has not been determined.

SIDE EFFECTS: Reported side effects include:

Serious side effects that have been reported are:



PREPARATIONS: Oral capsules: 5, 10, and 25 mg

STORAGE: Capsules should be stored at room temperature, between 20 C to 25 C (68 F to 77 F).



  • For the treatment of mild to moderate anxiety disorders or symptoms: 5 to 10 mg by mouth 3-4 times daily.
  • For the treatment of severe anxiety disorders or symptoms: 20 to 25 mg by mouth 3-4 times daily.
  • For the management of preoperative apprehension and anxiety: 5 to 10 mg by mouth 3-4 times daily on days preceding surgery.

Dosing: Pediatrics

  • For the treatment of anxiety symptoms in children = 6 years to adolescents the usual daily recommended dose is 5 mg 2-4 times daily.
  • Dosage may be increased to 10 mg per day given in 2-3 divided doses if necessary.
  • Chlordiazepoxide is not recommended for use in children below the age of 6 years.

Dosing: Geriatric patients

  • The usual recommended dose is 5 mg 2 to 4 times daily.
Medically Reviewed by a Doctor on 12/22/2014

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