Childhood Acute Lymphoblastic Leukemia (cont.)

What is the treatment for recurrent childhood acute lymphoblastic leukemia (ALL)?

Standard treatment of recurrent childhood acute lymphoblastic leukemia (ALL) for leukemia that comes back in the bone marrow may include the following:

  • Combination chemotherapy.
  • Chemotherapy with or without total-body irradiation followed by a stem cell transplant, using stem cells from a donor.

Standard treatment of recurrent childhood acute lymphoblastic leukemia (ALL) for leukemia that comes back outside the bone marrow may include the following:

  • Chemotherapy and radiation therapy for cancer that comes back in the testicles only.
  • Combination chemotherapy and intrathecal chemotherapy with radiation therapy to the brain and/or spinal cord for cancer that comes back in the brain and spinal cord only.

Some of the treatments being studied in clinical trials for recurrent childhood ALL include the following:

  • New anticancer drugs and new combination chemotherapy treatments.
  • Combination chemotherapy and new kinds of targeted therapies.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent childhood acute lymphoblastic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug.

REFERENCE:

National Cancer Institute. "Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)." National Institutes of Health. 3 Feb. 2012. <http://www.cancer.gov/cancertopics/pdq/treatment/childALL/Patient/page1/AllPages>.


Last Editorial Review: 2/3/2012


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Childhood Acute Lymphoblastic Leukemia - Experience Question: Please describe your experience with childhood acute lymphoblastic leukemia.
Childhood Acute Lymphoblastic Leukemia - Family History Question: If your child has ALL, is there a family history or exposure to radiation? Please share your story.
Childhood Acute Lymphoblastic Leukemia - Signs Question: What were your child's signs and symptoms associated with ALL?
Childhood Acute Lymphoblastic Leukemia - Diagnosis Question: Please describe the tests that led to a diagnosis of ALL.
Childhood Acute Lymphoblastic Leukemia - Treatment Question: What types of treatment has your child experienced for ALL?

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