MedicineNet.com
About Us | Privacy Policy | Site Map
November 24, 2009
MedicineNet home Picture Slideshows Diseases and conditions Symptoms and signs Procedures and tests Medications Health and Living Picture Image Collection MedTerms medical dictionary
Font Size
A
A
A

Chest Pain (cont.)

The Lung

Pneumonia

An infection of the lung is called pneumonia, in which inflammation can cause fluid buildup within a segment of the lung tissue, decreasing its ability to transfer oxygen from air to the bloodstream.

Pneumonia presents with the typical symptoms of an infection:

  • fever

  • chills

  • malaise

There may also be:

  • cough,

  • shortness of breath, and

  • sputum production (coughing up mucus).

The chest pain is pleuritic, hurting when taking a deep breath.

Physical examination may find the patient to have abnormal vital signs consistent with an infection. The PR and RR may be elevated. A fever may be present. Listening to the chest may reveal decreased air entry in the area of the infection associated with crackles and occasionally wheezing because of inflammation and narrowing of the bronchial tubes.

A chest x-ray helps make the diagnosis, though the x-ray image sometimes lags behind the clinical findings by a day or two. Blood tests may be used to assess the severity of illness and may include a white blood cell count (markedly elevated or abnormally low counts may indicate more severe illness) and an arterial blood gas level to assess lung function.

Pneumonia may be caused by a virus or bacteria. The latter is treated with antibiotics, either by mouth or in the hospital by intravenous infusion. The general health and past medical history of the patient may guide the decision as to whether inpatient or outpatient therapy is most appropriate. For more, please read the Pneumonia article.

Pulmonary embolism

A blood clot to the lung can be fatal and is one of the diagnoses that should always be considered when a patient presents with chest pain.

While there is a classic presentation for pulmonary embolus of pleuritic chest pain, shortness of breath, and coughing up blood (hemoptysis), the more common presentation is much more subtle, and the diagnosis may be easily and unavoidably missed.

Risk factors for pulmonary embolus include:

  • prolonged inactivity like a long trip in a car or airplane

  • recent surgery or fracture

  • birth control pills (especially associated with smoking)

  • cancer

  • pregnancy

Thrombophilia (thrombo=clot + philia= attraction) comprises a host of blood clotting disorders that place patients at risk for pulmonary embolus.

The pulmonary embolus begins in veins elsewhere in the body, usually the legs, though it can occur in the pelvis, arms, or the major veins in the abdomen. When a thrombus or blood clot forms, it has the potential to break free (now called an embolus) and float downstream, returning to the heart. It can pass through the heart and into the pulmonary circulation system, eventually becoming lodged in the branches of the pulmonary artery and cutting off blood supply to part of the lung. This decreased blood flow doesn't allow enough blood to pick up oxygen in the lung, and the patient can become markedly short of breath.

As mentioned above, the common complaints include:

  • pleuritic chest pain from the inflamed lung,

  • bloody sputum, and

  • shortness of breath.

The patient can also have anxiety and sweat profusely. Depending upon the size of the clot, the initial presentation may be fainting (syncope) or a passing-out spell.

Depending on the severity of the embolus and the amount of lung tissue at risk, the patient may present critically ill (in extremis) with markedly abnormal vital signs, or may appear rather normal. Physical examination may not be helpful, and the diagnosis is made upon clinical suspicion based on history and risk factors.

The diagnosis may be made directly with imaging of the lungs or indirectly by finding a clot elsewhere in the body. The strategy used to make a diagnosis will depend upon each individual patient's situation, but there are some general tools available.

D-dimer is a blood test that can measure breakdown products of blood clots in the body but cannot differentiate a pulmonary embolus from a healing scar from surgery, or a bruise from falling. If this test is negative, then a pulmonary embolus can usually be excluded.

Lungs can be imaged with a ventilation-perfusion scan or a CT scan to look for a clot. Each test has its benefits and limitations, and use of these tests is dependent upon the clinical situation. If there are technical issues so that the lungs cannot be imaged, an ultrasound of the legs may be performed to look for a thrombus; the concept is that if the symptoms are present of a pulmonary embolus and a clot is found in the leg, then the diagnosis can be inferred. Sometimes direct angiography of the pulmonary arteries may be performed.

The treatment for pulmonary embolus is anticoagulation using either heparin or enoxaparin (Lovenox) initially, then transitioning to warfarin (Coumadin) for long-term treatment. The usual treatment course for anticoagulation for a pulmonary embolus is three to six months.

The lungs and heart can stop working if there is a large enough clot load. Aside from the basics of oxygen, intravenous fluids, and medicines to support blood pressure, thrombolytic or clot busting therapy may be considered. In rare and extreme cases, lytic agents may be directly injected into the area of clot.

Pulmonary embolus should always be considered a life-threatening illness.

For additional information, please read the Pulmonary Embolism article.

The Heart



Next: Angina and heart attack »

Chest Pain - Cause

The MedicineNet physician editors ask:

What was the cause of your chest pain?

Anonymously share your comment to help others. Patient Discussions FAQs
See 16 Viewer Comments

Submit Your Comment


Printer-Friendly Format  |  Email to a Friend


Suggested Reading by Our Doctors
MedicineNet Doctors
  • Beta Blockers - Learn more about Beta Blockers, a drug that treats angina and other heart rhythm disorders, migraines, high blood pressure, panic attacks, and tremors. Generic and brand names are included in the article.
  • CT Scan (Computerized Axial Tomography) - CT Scan (Computerized Axial Tomography, CAT scan) is a procedure that assists in diagnosing tumors, fractures, bony structures, and infections in the organs and tissues of the body.
  • Pneumonia - Learn pneumonia symptoms, causes, treatment, signs, diagnosis and types: viral and bacterial (Pneumocystis carinii, Klebsiella, Mycoplasma, Chlamydia pneumoniae).

Latest Medical News


Heart Health

Get the latest treatment options.


Are you Depressed? Take the Quiz

Your Guide to Symptoms & Signs: Pinpoint Your Pain












Health categories:

Slideshows | Diseases & Conditions | Symptoms & Signs | Procedures & Tests | Medications | Health & Living | News & Views | Medical Dictionary

Popular health centers:

Allergies | Arthritis | Cancer | Diabetes | Digestion | Healthy Kids | Heart | Men's Health | Mental Health | Women's Health | More...

Publications:

ePublications (PDFs) | XML News via RSS | Audio Podcasts | Email Newsletters

MedicineNet.com:

About Us | Privacy Policy | Site Map | WebMD® | Medscape® | eMedicine® | eMedicineHealth® | RxList®

This website is certified by Health On the Net Foundation. Click to verify. This site complies to the HONcode standard for trustworthy health information:
verify here.

©1996-2009 MedicineNet, Inc. All rights reserved. Notices and Legal Disclaimer.
MedicineNet does not provide medical advice, diagnosis or treatment. See additional information.