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GENERIC NAME: CEVIMELINE - ORAL (seh-VIMM-eh-leen)

BRAND NAME(S): Evoxac

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to treat the symptom of dry mouth in patients with Sjogren's Syndrome. Cevimeline increases the activity of glands in the mouth and skin (e.g., salivary and sweat glands).

OTHER USES: This medication may also be used for dry mouth symptoms due to other causes.

HOW TO USE: This medication is taken by mouth, usually three times a day. It may be taken with or without food but is best absorbed on an empty stomach. If unusual sweating occurs while taking this medication, drink extra water throughout the day and consult your doctor or pharmacist.

SIDE EFFECTS: Nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, or trouble sleeping may occur. If these effects persist or worsen, notify your doctor. Tell your doctor immediately if you have any of these serious side effects: trouble breathing, fever, sore throat, painful or frequent urination, unusual joint or muscle pain. Tell your doctor immediately if you have any of these unlikely but serious side effects: chest pain, irregular heartbeat, easy bruising or bleeding, yellowing eyes or skin, stomach pain, mental/mood changes. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, including: allergies, liver or heart disease, breathing problems (e.g., asthma, bronchitis, COPD), eye problems (e.g., glaucoma, acute iritis), kidney stones, gall bladder problems (gall stones). This drug may make you dizzy or cause vision problems; use caution engaging in activities requiring alertness such as driving or using machinery especially at night or in poor light. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.






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  • Sjogren's Syndrome - Learn about Sjogren's syndrome, an autoimmune disease involving the abnormal production of extra antibodies that attack the glands and connective tissue. Primary Sjogren's syndrome only affects the glands, while secondary Sjogren's syndrome also involves the connective tissue. Symptoms may include dry eyes, dry mouth, rheumatoid arthritis, lupus, or scleroderma. Though there is no cure for Sjogren's syndrome, the symptoms may be treated by using lubricating eye ointments, drinking plenty of water, humidifying the air, and using glycerin swabs. Medications are also available to treat dry eye and dry mouth. Source:MedicineNet
  • Dry Mouth - Read about dry mouth causes (dehydration, diabetes, Sjogren's syndrome, medications for allergies and anxiety), symptoms (sore throat, raw tongue) and treatment. Source:WebMD Medical Reference from The Cleveland Clinic
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Last Editorial Review: 3/2/2005

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