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February 3, 2012
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Cervical Cancer
(Cancer of the Cervix)

Doctor to Patient

Who Should Get the HPV Vaccine?

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

Get the facts on the HPV virus and the cervical cancer vaccine. Human papillomavirus (HPV) infection of the cervix can lead to cervical cancer. A vaccine designed to prevent cervical cancer and other diseases caused by infection with HPVs was approved for use in the U.S. in June 2006. This is the first vaccine to be developed against a known risk factor for the development of a cancer.

While some HPV types infect the skin and cause benign warts and other lesions, about 40 types of HPVs can infect the genital tract. Genital HPV infection is very common in the general population; estimates suggest that up to 50% of all sexually active people will be infected at some point in their lives. In the majority of cases, the infection does not cause any symptoms, but in some women, HPV infection can progress to cause precancerous and cancerous lesions of the uterine cervix. HPVs that infect the genital area are also associated with other less common genital cancers in men and women such as cancers of the anus, vagina, penis, and vulva. HPV infection also causes genital warts in men and women.

The most common HPV types that infect the genital area are HPV types 6, 11, 16, and 18. Among these, HPV types 6 and 11 are most commonly associated with benign lesions, such as genital warts and mild precancerous changes of the cervix. In contrast, HPV types 16 and 18 are the types found in the majority of cancers as well as in severe precancerous changes of the cervix. The vaccine, called Gardasil, targets these four common HPV types.


Top Searched Cervical Cancer & HPV Terms:

stages, survival rate, Pap smear, colposcopy, cervical dysplasia, cure
Doctor to Patient

Cervical cancer facts

  • Causes and risk factors for cervical cancer have been identified and include human papillomavirus (HPV) infection, having many sexual partners, smoking, taking birth control pills, and engaging in early sexual contact.


  • HPV infection may cause cervical dysplasia, or abnormal growth of cervical cells.


  • Regular pelvic exams and Pap testing can detect precancerous changes in the cervix.


  • Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery.


  • The most common symptoms and signs of cervical cancer are abnormal bleeding and pelvic pain.


  • Cervical cancer can be diagnosed using a Pap smear or other procedures that sample the cervix tissue.


  • Chest X-rays, CT scan, MRI, and a PET scan may be used to determine the stage of cervical cancer.


  • Cancer of the cervix requires different treatment than cancer that begins in other parts of the uterus.


  • Treatment options for cervical cancer include radiation therapy, surgery, and chemotherapy.


  • Two vaccines, Gardasil and Cervarix, are available to prevent HPV infection.


  • The prognosis of cervical cancer depends upon the stage and type of cervical cancer and the tumor size.


Patient Discussions

Viewers share their comments

Cervical Cancer - Symptoms Question: What symptoms did you experience with cervical cancer?
Cervical Cancer - Treatments Question: What treatment has been effective for your cervical cancer?
Cervical Cancer - Risk Factors at Time of Diagnosis Question: Did you have any of the risk factors for cervical cancer at the time of your diagnosis? If so, what were they?

MedicineNet Doctors

Suggested Reading on Cervical Cancer by Our Doctors

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Cervical Cancer

What is chemotherapy?

Chemotherapy (also called chemo) is a type of cancer treatment that uses drugs to destroy cancer cells.

How does chemotherapy work?

Chemotherapy works by stopping or slowing the growth of cancer cells, which grow and divide quickly. But it can also harm healthy cells that divide quickly, such as those that line your mouth and intestines or cause your hair to grow. Damage to healthy cells may cause side effects. Often, side effects get better or go away after chemotherapy is over.

What does chemotherapy do?

Depending on your type of cancer and how advanced it is, chemotherapy can:

  • Cure cancer - when chemotherapy destroys cancer cells to the point that your doctor can no longer detect them in your body and they will not grow back.
  • Control cancer - when chemotherapy keeps cancer from spreading, slows its growth, or destroys cancer cell...

Read the Chemotherapy article »







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