Celiac Disease Symptoms

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A Doctor's View on Celiac Disease Symptoms

Celiac disease is an uncommon disease in which your immune system attacks the cells lining the small intestine. The reaction is provoked by gliadin, one of the proteins in gluten that is found in wheat and some other grains. The immune reaction results in inflammation and destruction of the intestinal lining cells. The destruction of the lining affects the ability of the lining to function normally, particularly in the absorption of food including macronutrients (fat, protein, and carbohydrates) and micronutrients (vitamins, and minerals). Thus, although some of the symptoms of celiac disease may be a result of the ongoing inflammation and destruction, most of the symptoms are the result of the malabsorption. The presence of celiac disease usually is suspected on the basis of symptoms, but the diagnosis is confirmed with a combination of blood tests and biopsy of the intestine. It is common in both men and women.


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Medically Reviewed by a Doctor on 12/12/2013