Celiac Disease (cont.)
Bhupinder Anand, MD
In this Article
What if individuals don't respond to gluten free diet?
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Failure to respond to a gluten free diet can be due to several reasons:
What is refractory celiac disease?
Refractory celiac disease is a rare condition in which the symptoms of celiac disease (and the loss of villi) do not improve despite many months of a strict gluten free diet. Before making a diagnosis of refractory celiac disease it is important to exclude complications of celiac disease and other co-existing conditions that can produce similar symptoms and biopsy findings.
Refractory celiac disease is believed to consist of two different entities, one which is relatively benign and one which becomes malignant or cancerous. Special examination of intestinal tissue from patients with refractory celiac disease can differentiate between the two entities.
What is the treatment for refractory celiac disease?
The treatment of refractory celiac disease is first to make sure that all gluten is eliminated from the diet. If there still is no improvement, medications are used.
Unfortunately in some patients with refractory celiac disease, malabsorption and malnutrition progress despite drugs. In these patients the intravenous route is the only way to deliver nutrition. Total parenteral nutrition (TPN) is a way of delivering calories, carbohydrates, amino acids, and fat in liquid solutions via a catheter that has been inserted and secured into a vein.
Reviewed by Bhupinder Anand, MD on 6/28/2011
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Celiac Disease - Symptoms Question: The symptoms of celiac disease can vary greatly from patient to patient. What were your symptoms at the onset of your disease?
Celiac Disease - Diagnosis Question: How was your celiac disease diagnosed?
Celiac Disease - Treatment Question: What kinds of treatment, including changes in diet, have you tried for your celiac disease?
Celiac Disease - Diet Question: Discuss the dietary changes you've made to manage your celiac disease. Has your condition improved?
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