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Celiac Disease (cont.)

Who should undergo antibody blood tests for celiac disease?

Some experts recommend that antibody blood tests be used to screen healthy persons with no signs or symptoms for celiac disease. In Italy, where celiac disease is common, all children are screened for celiac disease. Experts in the United States do not recommend screening healthy persons for celiac disease. Antibody blood tests are only recommended for individuals with a higher likelihood than normal of having celiac disease. These patients are:

  1. Patients with chronic diarrhea (diarrhea that does not resolve in three weeks), increased amount of fat in the stool (steatorrhea), and weight loss

  2. Patients with excess gas, bloating, and abdominal distension

  3. First and second degree relatives of patients who have celiac disease

  4. Children with growth retardation

  5. Patients with unexplained iron deficiency anemia

  6. Patients with skin rashes suggestive of dermatitis herpetiformis

  7. Patients with recurrent painful mouth sores (aphthous stomatitis)

  8. Patients with disease known to be associated with celiac disease. Examples of these diseases include insulin-dependent diabetes mellitus, autoimmune thyroid disease, rheumatoid arthritis, systemic lupus, ulcerative colitis, etc.

Why is it important to accurately diagnose celiac disease?

Diagnosis of celiac disease should be firmly established before commencing treatment with a gluten free diet for several reasons.

  1. The gluten free diet is a life-long and tedious commitment that should not be taken lightly. It is more costly than a normal diet and has significant social implications for dining out.

  2. Patients with irritable bowel syndrome (IBS) may experience improvements in bloating, abdominal pain, and diarrhea with a gluten free diet. These patients may be misdiagnosed as having celiac disease. Without confirmation of celiac disease by small intestinal biopsy, they may be unnecessarily committed to life-long gluten restriction.

  3. A gluten free diet can lower blood antibody levels and allow the microscopic appearance of the small intestine to lose the typical appearance of celiac disease, complicating subsequent efforts at making a firm diagnosis of celiac disease.


Next: How are malabsorption and malnutrition evaluated in celiac disease? »

Celiac Disease - Symptoms at Onset of Disease

The MedicineNet physician editors ask:

The symptoms of celiac disease can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

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